Mental Health

Persistent Depressive Disorder

Persistent depressive disorder (dysthymia) is chronic depression lasting two years or more, with less intense but long-lasting symptoms.

Symptoms

Low mood most days, low energy, poor self-esteem, difficulty with decisions, hopelessness, and sleep or appetite changes.

Causes and risk

Chronic stress, early adversity, genetics, and co-occurring anxiety or medical illness.

How it is evaluated

Symptom timeline, prior treatments, daily functioning, and screening for overlapping major depressive episodes.

Treatment

Therapy (CBT or interpersonal), medication, and structured daily routines with consistent follow-up.

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